A routine trip to the piano store for Howard and Raj goes haywire when a piano falls from the fifth floor window and lands on Howard. Now fully paralyzed, Amy decides to loan Howard one of her lab monkeys to be used as a monkey butler. Howard and Melinda the Monkey’s bond grows to unhealthy levels as the simian servant grows jealous of Amy, Bernadette, and the Potato Penny. Sheldon wakes up sharing a bed with an unknown woman and a can of body spray on the nightstand, leading him to an occult bookstore to seek freedom from his moonlit curse. Leonard and Raj come up with a plan to rescue Howard, Amy, Bernadette, and the Potato Penny from the wrath of the monkey.